What are different types of intra-vaginal drug delivery system? Vaginal rings. Vaginal gel, creams and ointments. Vaginal gel, creams and ointments. Pessaries, tablets and suppositories. Bio-adhesive, micro-particulate drug delivery devices or systems. Others like foams, capsules, films, tampons, sponge and diaphragms. Advantages of intra – vaginal
Step 1 Wash your hands. Step 2 Remove any foil or plastic wrapping from the pessary. Step 3 Sit or lie down with your knees bent and legs apart. Step 4 Gently insert the pessary into the vagina as far as comfortably possible using your fingers. Step 5 Wash
According to British Pharmacopoeia (BP) - Pessaries are solid, single-dose preparations. They have various shapes, usually ovoid, with a volume and consistency suitable for insertion into the vagina. They contain one or more active substances dispersed or dissolved in a suitable bases that may
ADVANTAGES OF SUPPOSITORIES Over Oral Drug Administration: Avoid first pass metabolism Introduce drugs into the body Does not cause nausea and vomiting due to gastric irritation in case of oral therapy Used before surgery since oral therapy is restricted Beneficial for patients suffering from severe
Insertion of a suppository into the rectum results in a chain of effects leading to the bioavailability of the drug. The sequence of events leading to drug absorption from the anorectal area can be represented as follows: Drug in vehicle → Drug in colon fluids
After administration, the role of the suppository is to release the active principle, either by melting due to body temperature or by dissolving in the local mucosal fluids and then to release the active ingredient so it is free to produce a local effect
Step 1 Wash your hand thoroughly with soap and water. Step 2 If the suppository is soft, hold it under cool water or place it in a refrigerator for a few minutes to harden it before removing the wrapper. Step 3 Remove the wrapper, if present. Step
“SUPPOSITORY” term is derived from the Latin term “Supponere” meaning “to place under”. ‘Suppository’ is a medicated, solid dosage form which is intended for insertion into body orifices where they melt, soften or dissolve and exert localized or systemic effects. The medicament is incorporated
English
Arabic
French
Portuguese
Russian
Spanish